The Genetic Polymorphism of TNF-α Associated with the Anti-TNF-α Therapy Used for COVID-19 Patients – Another Possible Approach

Objective: This work aimed of to review the implications anti-TNF-α therapy in COVID-19 patients associated with genetic polymorphism (TNF-α polymorphisms region-308) this pertinent cytokine Methodology: Electronic searches were carried out on PUBMED Central, BVS/BIREME, Web Science and The Cochrane Library aid key-words. Results: Twenty-six articles collected. Anti-TNF-α was interpreted evaluated. Conclusions: Although scarce information is available current literature, anti- TNF-α seems be a viable clinical approach for hospitalized who do not need oxygen supply. polymorphisms, although relevant, may useful further researched assess response different research groups.